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Chinese Name

中文名


瑞加德松

English Name

英文名


regadenoson

Alias

别名

Lexiscan;1-(6-Amino-9((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydofuran-2-yl)-9H-purin-2-yl)-N-methyl-1H-pyrazole-4-carboxamide hydrate;2-[(Methylamino)carbony]-1H-pyrazol-1-yl]-adenosine



CAS NO.


313348-27-5;875148-45-1

Formula

分子式


C15H20N806

M.W.

分子量


408.37

Class

分类


最新原料药


Regadenoson是一种A2A腺苷受体激动剂是一种冠状动脉血管扩张剂。
适应证:Lexiscan是一种药理学应激剂适用于在不能进行适当运动负荷患者中放射性核素心肌灌注显像(MPI)。
剂量和用法:Lexiscan推荐的剂量是5 mL (0.4 mg regadenoson)通过迅速静脉注射;随后立即用盐水和放射性药物冲洗。
禁忌证:有二级或三级AV阻滞,或窦房结功能失调患者不能给予Lexiscan除非患者 有功能良好的人工心脏起搏器 
不良反应:对Lexiscan最常见(发生率 ≥ 5%)不良反应是呼吸困难、头痛、面红、胸部不适、眩晕、心绞痛、胸痛、和恶心。
药物相互作用:甲基黄嘌吟类,如,咖啡因和茶碱,可能干扰Lexiscan的活性。 氨茶碱可能用于减轻严重和/或对Lexiscan的持久不良反应。



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